경부에서 전이성종양을 닮은 가성육종성 결절근막염의 증례보고
A Case of Pseudosarcomatous Nodular Fasciitis in Cervical Area Mimicking Metastatic Tumor
김민근, 송지영, 김성곤, 박영욱, 윤종상, 이석근, 이상신,
소속 상세정보
김민근 ( Kim Min-Geun ) - 강릉원주대학교 치과대학 구강악안면외과학교실
송지영 ( Song Ji-Young ) - 강릉원주대학교 치과대학 구강악안면외과학교실
김성곤 ( Kim Seong-Gon ) - 강릉원주대학교 치과대학 구강악안면외과학교실
박영욱 ( Park Young-Wook ) - 강릉원주대학교 치과대학 구강악안면외과학교실
윤종상 ( Yoon Jong-Sang ) - 강릉원주대학교 치과대학 구강병리학교실
이석근 ( Lee Suk-Keun ) - 강릉원주대학교 치과대학 구강병리학교실
이상신 ( Lee Sang-Shin ) - 강릉원주대학교 치과대학 구강병리학교실
KMID : 0829220110350020107
Abstract
The present case occurred in the cervical area of 51 years old male, who was generally healthy but recently complained of cervical swelling with mild pain. The tumor recently grew rapidly for 5 months. He was referred from local hospital in the diagnosis of metastatic tumor in cervical lymph. In the biopsy procedure, the tumor mass was ill-defined and not associated with cervical lymph node. The microsection showed a highly proliferative fibrous tissue infiltrative growth into the periphery. The spindle tumor cells were stained red in Masson trichrome stain, and strongly positive for PCNA and β-catenine, and partly positive for α-smooth muscle actin (α-SMA), but negative for S-100 and desmin. The differential diagnosis in primary biopsy examination was made as leiomyosarcoma, malignant schwannoma, and mesenchymal sarcoma. Under the diagnosis of sarcoma the patient was operated for tumor resection including cervical lymph nodes. The tumor mass was tightly attached on the lower border of left mandibular body. After the surgical operation the tumor tissue was more investigated with further immunohistochemical stainings, and discussed with several pathologists in Gangneung area. Finally the tumor was turned out to be a nodular fasciitis with pseudosarcomatous proliferation, and also confirmed that the pseudosarcomatous spindle cells belonged to the myofibroblasts originated from the fibrovascular fascial tissue. The present study demonstrated a rare case of nodular fasciitis, which should be differentially diagnosed from the malignant head and neck tumors.
키워드
Nodular fasciitis; Pseudosarcomatous proliferation
원문 및 링크아웃 정보
등재저널 정보